The Science
Two tracks. One framework.
Track One — Lifestyle Architecture
Built on five foundational bodies of evidence.
Track One synthesises the architecture of healthspan — the lifestyle interventions for which there exists robust, replicated, and audited evidence.
Blue Zones — Power 9
Dan Buettner's nine common denominators across populations with verified extreme longevity. Diet, movement, social rings, purpose.
ACLM Six Pillars
American College of Lifestyle Medicine's clinical framework: nutrition, physical activity, sleep, stress, social, substance avoidance.
Peter Attia, MD — Five Pillars
Outlive: exercise, nutrition, sleep, emotional health, and exogenous molecules under physician oversight. The framework that crystallised the field.
WHO Intrinsic Capacity
Six functional capacities — locomotion, cognition, vitality, sensory, psychological, continence — operationalised for population health.
2024 PMC Systematic Review
Thirty-five RCTs, n ≈ 25,000. Multidimensional lifestyle interventions outperform single-pillar protocols by a wide margin.
The disproportionate gains emerge only when all five are delivered simultaneously.
Track Two — Cellular Rejuvenation
We do not start out young. We work our way back to it.
Beyond lifestyle, the science of partial cellular reprogramming is advancing rapidly. Yamanaka factors. In-vivo trials. The first human studies. The Aevum Standard tracks this work as Track Two — integrated when it crosses the evidentiary threshold, not before.
Read the deep dive →